Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primer on molecular imaging technology.

Craig S Levin1

  • 1Division of Nuclear Medicine, Department of Radiology and Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building, Room R354, Stanford, CA 94305-5344, USA. cslevin@stanford.edu

European Journal of Nuclear Medicine and Molecular Imaging
|December 13, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of deep learning and particle smoother EM methods for estimation of Rb-82 myocardial perfusion PET kinetic parameters.

Medical physics·2026
Same author

Maximum likelihood estimation yields accurate line-of-response assignment for positron + prompt gamma ray events in multiplexed PET (mPET).

Biomedical physics & engineering express·2026
Same author

Influence of scintillation light confinement on depth-of-interaction measurement performance in a single-ended readout PET detector.

Physics in medicine and biology·2026
Same author

Using multimodal PET+MR data as conditional generative adversarial network inputs improves pseudo-CT and attenuation correction estimates for brain PET/MR.

American journal of nuclear medicine and molecular imaging·2026
Same author

Context-Aware Transformer GAN for Direct Generation of Attenuation and Scatter Corrected PET Data.

IEEE transactions on radiation and plasma medical sciences·2026
Same author

Detector design for a high-resolution and high-sensitivity breast-dedicated multiplexed PET (<i>m</i>PET) scanner.

Physics in medicine and biology·2026
Same journal

Intrahepatic cholangiocarcinoma treated with glass yttrium-90 radioembolization: A histopathologic study.

European journal of nuclear medicine and molecular imaging·2026
Same journal

Novel PET tracers to distinguish the nature of residual masses after the completion of chemotherapy in metastatic testicular germ cell tumours: A systematic review.

European journal of nuclear medicine and molecular imaging·2026
Same journal

Diagnostic impact of 18F-FDG PET/MRI over PET/CT in histiocytoses: a prospective comparative study.

European journal of nuclear medicine and molecular imaging·2026
Same journal

Clinical performance of [<sup>68</sup>Ga]Ga-DOTA-FAPI-04 PET/CT in detecting recurrent disease in medullary thyroid carcinoma: a comparative analysis with [<sup>18</sup>F]F-FDG and [<sup>68</sup>Ga]Ga-DOTATATE PET/CT, alongside identification of suitable candidates for targeted radionuclide therapy.

European journal of nuclear medicine and molecular imaging·2026
Same journal

Whole-brain metabolic activity on pretreatment [18 F]FDG PET/CT provides prognostic information beyond metabolic tumour burden in patients with breast cancer.

European journal of nuclear medicine and molecular imaging·2026
Same journal

Redefining robotic image-guidance - tomographic visualization of lesions during prostate cancer surgery via gantry-free robotic SPECT.

European journal of nuclear medicine and molecular imaging·2026
See all related articles

This article reviews key in vivo molecular imaging technologies, including positron emission tomography, single-photon emission computed tomography, and bioluminescence imaging, detailing their instrumentation and performance for research applications.

Area of Science:

  • Medical Imaging
  • Molecular Imaging
  • Biotechnology

Background:

  • Diverse technologies exist for molecular and cellular imaging across in vivo, ex vivo, and in vitro settings.
  • Molecular imaging research relies on advanced instrumentation for accurate in vivo studies.

Purpose of the Study:

  • To detail the instrumentation technologies for three key in vivo molecular imaging modalities.
  • To provide an overview of positron emission tomography, single-photon emission computed tomography, and bioluminescence imaging.
  • To discuss performance parameters, state-of-the-art instrumentation, and multimodal integration.

Main Methods:

  • Review of instrumentation principles for positron emission tomography (PET).
  • Description of single-photon emission computed tomography (SPECT) system technologies.

Related Experiment Videos

  • Overview of bioluminescence imaging (BLI) instrumentation and applications.

    • Main Results:

    • Detailed explanations of how PET, SPECT, and BLI systems function.
    • Discussion of critical performance metrics for each imaging modality.
    • Presentation of current advancements in instrumentation for these techniques.

    Conclusions:

    • The article provides a comprehensive guide to in vivo molecular imaging instrumentation.
    • Understanding these technologies is crucial for advancing molecular imaging research in humans and small animals.
    • Integration of multiple modalities offers enhanced insights in molecular imaging studies.