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Updated: Aug 14, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Magnetic resonance imaging changes in a patient with migraine attack and transient global amnesia after cardiac
Andres Fernandez1, Fred Rincon, Sean P Mazer
1Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Abstract:
The presence of magnetic resonance imaging (MRI) abnormalities in patients with transient global amnesia has been an interesting phenomenologic finding. Several theories surround the occurrence of this syndrome, but little is known about its true physiopathology. We present a case of transient global amnesia after cardiac catheterization associated with migraine headache and MRI changes compatible with an ischemic insult. A discussion on potential explanations for this finding is made, as well as a review of the pertinent literature.
Insights
Transient global amnesia (TGA) can manifest with magnetic resonance imaging (MRI) abnormalities. This case report details TGA following cardiac catheterization, linked to migraine and ischemic changes on MRI.
Area of Science:
- Neurology
- Neuroradiology
- Cardiology
Background:
- Transient global amnesia (TGA) is a temporary memory loss syndrome with unclear pathophysiology.
- Magnetic resonance imaging (MRI) findings in TGA are increasingly recognized but not fully understood.
- Cardiac catheterization is a potential trigger for neurological events.
Observation:
- A patient experienced TGA after cardiac catheterization.
- The patient also reported a concurrent migraine headache.
- Cerebral MRI revealed abnormalities consistent with an ischemic insult.
Findings:
- The case links TGA, migraine, and ischemic changes on MRI.
- This association suggests a potential ischemic mechanism in TGA under specific circumstances.
- The findings challenge existing theories on TGA etiology.
Implications:
- This case highlights the importance of neuroimaging in TGA evaluation.
- It suggests a possible link between cardiovascular procedures, migraine, and ischemic TGA.
- Further research is needed to elucidate the physiopathology of TGA and its potential ischemic basis.
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