Norrie's disease vs. PHPV: one family's dilemma

This paper presents the numerous similarities between Norrie's disease and bilateral persistent hyperplastic primary vitreous. A description of each disease is given, as well as a case report which demonstrates the difficulty in distinguishing the two disease processes when there is a negative family history of blindness. A discussion section focuses on the need for a better differential protocol for Norrie's disease, which would aid the clinician when a family history of blindness is absent.