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Updated: Aug 14, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Novel Allylic Oxidation of alpha-Cedrene to sec-Cedrenol by a Rhodococcus Strain
H Takigawa1, H Kubota, H Sonohara
1Tochigi Research Laboratories of Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-34, and Wakayama Research Laboratories of Kao Corporation, 1334 Minato, Wakayama 640, Japan.
Abstract:
A bacterial strain, designated KSM-7358, that can use alpha-cedrene for growth was isolated. The strain was identified as a member of the genus Rhodococcus and catalyzed the novel allylic oxidation of alpha-cedrene regiospecifically to produce (R)-10-hydroxycedrene (sec-cedrenol) with a very high yield. alpha-Curcumene was also produced as a possible metabolite of sec-cedrenol. A possible pathway for the microbial conversion of alpha-cedrene to sec-cedrenol and alpha-curcumene is proposed.
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