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Updated: Aug 14, 2026

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
Published on: May 20, 2016
[Computational fluid dynamics simulations of the airflow in the human nasal cavity]
P Castro Ruiz1, F Castro Ruiz, A Costas López
1Fundación Pública Hospital do Salnés, Vilagarcía de Arousa, Pontevedra. coscas@wanadoo.es
Objective:
This study represents an attempt to simulate the complex three-dimensional airflow pattern in the human nasal passageways.
Materials And Methods:
In the present study the computational Fluid Dynamics (CFD) have been used. The CFD solved numerically the flow governing equations. The CFD demonstrated to be a very efficient tool for researching on nasal flow.
Results:
By means of CT scan, an anatomic accurate three-dimensional representation of the human nasal cavity was obtained. Based on this model the influence of the inspiration and at the expiration at the flow pattern has been reviewed. The flow pattern is visualized by the velocity, pressure and turbulence intensity fields.
Conclusions:
The flow patterns show the channel effect of turbinates and the influence of the breathing phase.
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