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Updated: Aug 10, 2026
Subtype-selective Electroporation of Cortical Interneurons
Published on: August 18, 2014
Expression of GAD mRNA in GABA interneurons of the rat medial frontal cortex
S Rétaux1, J F Julien, M J Besson
1Laboratoire de Neurochimie-Anatomie, Université Paris 6-Pierre et Marie Curie, France.
Abstract:
The distribution of glutamic acid decarboxylase (GAD) mRNA containing cells was studied in the rat medial frontal cortex (MFC). The neurons labelled by the 35S-labelled cDNA probe were distributed uniformly throughout all the layers and represented 16% of the total neuronal population. It was possible to distinguish two cell populations expressing high and low levels of GAD mRNA corresponding to 63% and 27% of labelled cells, respectively. Concerning the laminar distribution of these two populations of GAD mRNA containing neurons, no marked difference was observed between the various areas of the MFC.
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