Related Experiment Video
Updated: Aug 7, 2026
09:11
A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
Chlamydia trachomatis infection in chronically hemodialyzed patients
A Bednarek-Skublewska1, M Majdan, M Dryglewska
1Department of Nephrology, University Medical School, Lublin, Poland. anna.bednarek@gambro.pl
Roczniki Akademii Medycznej W Bialymstoku (1995)
|December 20, 2005
Summary
Chlamydia trachomatis (Ch. trachomatis) infection, linked to reactive arthritis, was prevalent in 41% of dialysis patients. Antibodies were more common in women, especially younger ones, but no link to renal osteodystrophy was found.
Area of Science:
- Nephrology
- Infectious Diseases
- Rheumatology
Background:
- Chlamydia trachomatis (Ch. trachomatis) infection is associated with reactive arthritis (RA) in the general population.
- RA is a systemic inflammatory condition affecting joints, primarily the lower limbs.
- Dialysis patients represent a unique population with potential for chronic infections and complications.
Purpose of the Study:
- To determine the prevalence of Ch. trachomatis infection in dialysis patients.
- To analyze age and sex-specific infection rates.
- To investigate potential associations between Ch. trachomatis infection and renal osteodystrophy.
Main Methods:
- Study included 53 patients on hemodialysis (HD).
- Ch. trachomatis infection was assessed by detecting IgG antibodies.
- Biochemical markers for osteodystrophy, inflammation, and malnutrition were measured.
Main Results:
- 41% of patients tested positive for anti-Ch. trachomatis IgG antibodies.
- Antibody levels were significantly higher in seropositive patients.
- IgG antibodies were more frequent in women (60%) than men (29%), particularly in younger women.
- Seropositive women showed lower calcium, phosphorus, and transferrin saturation levels.
- No significant difference in C-reactive protein (CRP) was observed between seropositive and seronegative groups.
Conclusions:
- Elevated IgG antibodies for Ch. trachomatis are common in hemodialysis patients, suggesting past infection.
- The infection marker was more prevalent in women, particularly younger ones.
- No correlation was found between Ch. trachomatis infection and renal osteodystrophy in this cohort.
Related Concept Videos
01:29Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
01:24Hemodialysis II: Procedure and Complications
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
01:28Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
01:18Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.