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Updated: Aug 14, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Successful treatment of MRSA otorrhoea: a case report
1Department of Otolaryngology, Royal Surrey County Hospital, Guildford, and the Department of Otolaryngology, Epsom & St Helier University Hospitals NHS Trust, Epsom, UK. huntpickering@aol.com
Abstract:
Infection with methicillin-resistant Staphylococcus aureus (MRSA) is increasing. It may be community or hospital acquired and is characteristically difficult to eradicate. Here we report a case of a two-year-old girl who sustained a traumatic tympanic membrane perforation following a minor burns injury. She was seen as an out-patient in a burns unit and subsequently developed MRSA otorrhoea. This was treated with a two-week course of fusidic acid topical drops. At three-week follow up the tympanic membrane had healed and the infection had healed completely. Fusidic acid is safe and effective in the treatment of MRSA otorrhoea. We need to maintain vigilance in the treatment of otorrhoea, as MRSA may become an increasingly common pathogen in the future.
Insights
A two-year-old girl with MRSA otorrhoea, a difficult-to-treat infection, was successfully treated with fusidic acid drops. This case highlights fusidic acid
Area of Science:
- Otolaryngology
- Infectious Diseases
- Dermatology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) infections are rising globally.
- MRSA can be acquired in the community or healthcare settings and is notoriously hard to treat.
- Otorrhoea, or ear discharge, requires careful management due to potential complications.
Observation:
- A pediatric case involving a two-year-old girl with a traumatic tympanic membrane perforation after a burn injury.
- The patient developed methicillin-resistant Staphylococcus aureus (MRSA) otorrhoea following outpatient treatment in a burns unit.
- The MRSA otorrhoea presented a significant clinical challenge due to the pathogen's resistance.
Findings:
- Successful treatment of MRSA otorrhoea was achieved using a two-week course of topical fusidic acid drops.
- Complete healing of the tympanic membrane perforation and resolution of the infection were observed at three-week follow-up.
- Fusidic acid demonstrated safety and efficacy in managing this specific case of MRSA ear infection.
Implications:
- Topical fusidic acid is a viable and effective therapeutic option for MRSA otorrhoea.
- Vigilance in diagnosing and treating otorrhoea is crucial as MRSA emerges as a more frequent pathogen.
- This case underscores the importance of considering resistant organisms in ear infections, particularly in vulnerable populations.
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