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DNA-affinity-purified Chip (DAP-chip) Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
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Targeted discovery tools: proteomics and chromatin immunoprecipitation-on-chip

Xavier Le Guezennec1, Arie B Brinkman, Michiel Vermeulen

  • 1Nijmegen Center for Molecular Life Sciences, Department of Molecular Biology, Radboud University Nijmegen, Geert Grooteplein 30, Nijmegen, the Netherlands.

BJU International
|December 20, 2005
PubMed

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Chromatin Immunoprecipitation- ChIP

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Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
Chromatin Immunoprecipitation
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