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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Invasive treatment of coronary artery disease in octogenarians
Ewa Gaszewska-Zurek1, Paweł Zurek, Joanna Ciosek
1III Klinika Kardiologii Slaskiej Akademii Medycznej, ul. Ziołowa 47, 40-635 Katowice, Poland. pawewazurek@poczta.onet.pl
Insights
Invasive treatments for coronary artery disease in octogenarians are feasible and safe. Percutaneous coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) show acceptable risks and satisfactory outcomes in elderly patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Coronary artery disease (CAD) frequently affects patients over 80 years old.
- The efficacy and safety of invasive treatments in this demographic remain a critical clinical question.
Purpose of the Study:
- To compare one-year clinical outcomes of percutaneous coronary angioplasty (PTCA) versus coronary artery bypass grafting (CABG) in octogenarians.
- To evaluate outcomes in octogenarians compared to a younger control group (60-65 years).
Main Methods:
- Retrospective analysis of 63 patients over 80 undergoing PTCA or CABG for CAD.
- Comparison with 40 younger patients (60-65 years) treated similarly.
- Assessment of procedural risks, complications, and one-year clinical status.
Main Results:
- In octogenarians, 39 PTCA and 24 CABG procedures were performed.
- In-hospital mortality was 3%, with 18 periprocedural complications.
- One-year follow-up revealed 6 deaths, with higher recurrent angina rates after PTCA than CABG.
Conclusions:
- Invasive treatment for coronary artery disease in octogenarians is feasible.
- Satisfactory clinical outcomes and acceptable procedural risks were observed in this elderly population.
Introduction:
There are many patients aged over 80 years among those hospitalised for coronary artery disease (CAD). The unanswered question is whether invasive treatment of such patients is effective and safe.
Aim:
To assess and compare one-year clinical outcomes after percutaneous coronary angioplasty (PTCA) and surgical coronary artery bypass grafting (CABG) in patients aged over 80 years and in younger patients.
Method:
There were 63 patients aged over 80 years suffering from CAD who underwent either PTCA or CABG. The control group consisted of 40 patients aged 60-65 years treated in the same way. Data on medical history, cardiovascular risk factors, and angiographic findings were analysed. The potential risks of the procedures, post-procedural complications as well as the clinical status at the end of one-year follow-up were evaluated.
Results:
There were 24 surgical revascularisation procedures and 39 PCIs performed in the very old patients. Stable angina was found in 29 cases, unstable angina in 19 and acute myocardial infarction in 15 patients. There were three in-hospital deaths and 18 periprocedural complications were noted. During the one-year follow-up period six deaths occurred, persistent or recurrent angina was found in 11 patients after PCI and two after CABG. There were no deaths in the control group and the incidence of minor complications was similar to the senile group. In younger patients who underwent CABG, CCS class at one year was lower than in the very old ones.
Conclusions:
The invasive treatment of coronary artery disease in octogenarians is feasible with satisfactory results and acceptable procedural risks.
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