Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dampening inflammation.

Peter M Henson1

  • 1Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver Colorado 80206, USA. hensonp@njc.org

Nature Immunology
|December 22, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatial Heterogeneity of Macrophages in the Human Lung.

bioRxiv : the preprint server for biology·2025
Same author

Slamf7 is dispensable in mouse models of acute lung injury.

ERJ open research·2024
Same author

A LTB<sub>4</sub>/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease.

iScience·2024
Same author

TNFα: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease.

Frontiers in immunology·2024
Same author

Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation.

American journal of physiology. Lung cellular and molecular physiology·2023
Same author

Cigarette smoke-induced airspace disease in mice develops independently of HIF-1α signaling in leukocytes.

American journal of physiology. Lung cellular and molecular physiology·2022
Same journal

Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer.

Nature immunology·2026
Same journal

Mechanosensing by T cells promotes a tissue-resident memory transcriptional program.

Nature immunology·2026
Same journal

Editorial Expression of Concern: Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.

Nature immunology·2026
Same journal

Inflammatory immune modulators of AML lung infiltration and respiratory failure.

Nature immunology·2026
Same journal

The neuroimmune system and cognition.

Nature immunology·2026
Same journal

Critical connections.

Nature immunology·2026
See all related articles

This review explores how to reduce or prevent inflammation, examining natural processes and anti-inflammatory therapies. It highlights that while inflammation can be harmful, it is also a natural and essential biological response.

Area of Science:

  • Immunology
  • Pharmacology
  • Pathophysiology

Background:

  • Inflammation is a complex biological response often implicated in disease.
  • Current understanding frequently views inflammation solely as a detrimental process.

Purpose of the Study:

  • To review mechanisms for reducing, inhibiting, or preventing inflammation.
  • To explore the dual nature of inflammation: its essential beneficial roles and its pathological consequences.
  • To discuss the manipulation of inflammatory processes for therapeutic benefit.

Main Methods:

  • Literature review of natural anti-inflammatory processes.
  • Analysis of established and potential anti-inflammatory therapeutic strategies.
  • Synthesis of current research on the balance of inflammatory responses.

Related Experiment Videos

Main Results:

  • Identification of various natural and therapeutic pathways for inflammation control.
  • Recognition that inflammation, while often pathological, is fundamentally a necessary biological process.
  • Exploration of the intricate balance between beneficial and detrimental aspects of inflammation.

Conclusions:

  • Inflammation is a double-edged sword, essential for health but implicated in disease.
  • Understanding the balance of inflammation is key to developing effective anti-inflammatory therapies.
  • Future research should focus on modulating inflammatory responses rather than complete suppression.