Related Experiment Videos
Electronic crossmatching
1Department of Hematology, Blood Bank and Apheresis Unit, Ankara University, School of Medicine, Sihhiye, Turkey. arslan@medicine.ankara.edu.tr
Transfusion Medicine Reviews
|December 24, 2005
Summary
Electronic crossmatching (XM) streamlines pretransfusion testing by verifying ABO compatibility and detecting antibodies. This method, introduced in 1992, offers an efficient alternative to traditional crossmatch procedures.
Area of Science:
- Transfusion Medicine
- Immunology
- Laboratory Science
Background:
- Routine pretransfusion testing includes the crossmatch (XM) to ensure ABO compatibility and detect clinically significant antibodies.
- Traditional XM methods have evolved, leading to abbreviated procedures like immediate spin XM and antiglobulin XM.
- The antiglobulin phase of XM is often optional, particularly when no significant antibodies are detected.
Purpose of the Study:
- To summarize the fundamental principles of electronic crossmatching (XM).
- To outline current guidelines and regulatory requirements for implementing electronic XM.
- To provide recommendations for the successful adoption of electronic XM in transfusion services.
Main Methods:
- Review of the evolution and modifications of crossmatch procedures.
- Discussion of immediate spin XM and antiglobulin XM techniques.
- Exploration of the principles and implementation of electronic crossmatching.
Main Results:
- Electronic crossmatching was first implemented in 1992.
- The paper provides a comprehensive overview of electronic XM, including its benefits and requirements.
- Current guidelines and regulatory aspects of electronic XM are discussed.
Conclusions:
- Electronic crossmatching represents a significant advancement in pretransfusion testing efficiency.
- Adherence to established principles, guidelines, and regulatory standards is crucial for effective implementation.
- The paper offers practical recommendations to facilitate the adoption of electronic XM.