Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tethered cord syndrome.

F Rinaldi1, F A Cioffi, L Columbano

  • 1Department of Neuroradiology, Second University of Naples Medical School, Naples, Italy.

Journal of Neurosurgical Sciences
|December 24, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationship between interleukin 1 (IL-1) genetic polymorphism and periimplantitis: systematic literature review and meta-analysis.

European review for medical and pharmacological sciences·2024
Same author

Development of an analytical platform for the affinity screening of natural extracts by SEC-MS towards PPARα and PPARγ receptors.

Analytica chimica acta·2024
Same author

Blood-brain barrier damage associates with glia-related cytokines in the cerebrospinal fluid of patients with Multiple Sclerosis.

Multiple sclerosis and related disorders·2024
Same author

Progesterone and its derivatives for the treatment of catamenial epilepsy: A systematic review.

Seizure·2023
Same author

Use of a proline-specific endopeptidase to reintroduce gluten in patients with non-coeliac gluten sensitivity: A randomized trial.

Clinical nutrition (Edinburgh, Scotland)·2022
Same author

Photo-crosslinking of hyaluronic acid with low-level laser therapy device: a new combined and innovative approach.

Journal of biological regulators and homeostatic agents·2021
Same journal

Impact of weak MGMT promoter methylation on the prognosis of patients with newly diagnosed glioblastoma.

Journal of neurosurgical sciences·2026
Same journal

Pressure under the knife: embracing equanimity in neurosurgery.

Journal of neurosurgical sciences·2026
Same journal

Normal pressure hydrocephalus as a mechanobiological disorder.

Journal of neurosurgical sciences·2026
Same journal

Efficacy and safety of gamma knife radiosurgery in the management of pediatric gliomas: a systematic review and meta-analysis.

Journal of neurosurgical sciences·2026
Same journal

Balancing benefits and risks: bevacizumab's role in postoperative recovery after spinal oncologic neurosurgery.

Journal of neurosurgical sciences·2026
Same journal

Neurosurgeons in Italy: results of a national census (2022-2024).

Journal of neurosurgical sciences·2026
See all related articles

Tethered cord syndrome (TCS) can manifest in adulthood with neurological deficits. Early diagnosis and surgical untethering are crucial for improving symptoms and preventing permanent disability.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pediatric Neurology

Background:

  • Tethered cord syndrome (TCS) is a spinal cord disorder caused by inelastic structures, often a short filum terminale, anchoring the spinal cord.
  • Associated conditions like spinal dysraphism, hydromielia, and Arnold-Chiari malformation can occur, but their etiological link to TCS requires further clarification.

Purpose of the Study:

  • To analyze neuroradiological findings in pediatric and adult patients with TCS.
  • To establish precise diagnostic criteria and therapeutic strategies, including conservative and surgical options.

Main Methods:

  • Retrospective analysis of neuroradiological findings in 14 patients (5 children, 9 adults).
  • Inclusion criteria: neurological disturbances at the conus medullaris level and evidence of spinal dysraphism.

Related Experiment Videos

  • Diagnostic modalities included X-ray, CT, CT-myelography, and MRI, with MRI identified as the preferred method.

    • Main Results:

    • TCS diagnosis typically occurs in childhood but can present insidiously in adulthood with symptoms like gait disturbances, muscle atrophy, sensory loss, and pain.
    • MRI is the diagnostic method of choice.
    • Surgical untethering is recommended and can improve pain, ambulation, and bladder function.

    Conclusions:

    • Sphincter dysfunction may persist even after surgery.
    • Prophylactic surgery is advisable due to the risk of rapid deterioration and incomplete neurological recovery.
    • Long-term follow-up is essential for patients, especially those not undergoing surgery.