Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Odor perception in patients with mood disorders.

Sandrine Lombion-Pouthier1, Pierre Vandel, Sylvie Nezelof

  • 1Laboratoire de Neurosciences, Place Leclerc, Université de Franche-Comté, 25030 Besançon Cedex, France.

Journal of Affective Disorders
|December 27, 2005
PubMed
Summary

Psychiatric disorders like depression, anorexia, and addiction show distinct olfactory impairments. These differences in smell perception may indicate specific brain issues underlying these mood-related conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Late-life difficult-to-treat depression and dementia subtypes: a naturalistic cohort study using electronic health records.

Frontiers in psychiatry·2026
Same author

Differential Factor-Level MADRS Response Associated With Seizure Duration in Electroconvulsive Therapy: Exploratory Findings.

The journal of ECT·2026
Same author

Adverse childhood experiences and care-seeking for depression: evidence from a population-based cohort.

Journal of affective disorders·2026
Same author

Optimizing antidepressant use in geriatric depression: expert consensus from French societies of geriatrics, old age psychiatry, and clinical pharmacy (SFGG, SF3PA, and SFPC).

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Objective assessment of familiarity in music using imagery and EEG-based machine learning.

Scientific reports·2026
Same author

Is ageism among prescribers an influential factor in the management of depression in the elderly? A vignette-based study.

Family practice·2026

Area of Science:

  • Neuroscience
  • Psychiatry
  • Sensory Perception

Background:

  • Olfaction is linked to emotion, yet its role in psychiatric disorders with mood disturbances is poorly understood.
  • Investigating olfactory perception can reveal cerebral impairments in these conditions.

Purpose of the Study:

  • To identify specific olfactory perception characteristics in patients with psychiatric disorders.
  • To correlate these olfactory deficits with potential underlying brain impairments.

Main Methods:

  • Compared olfactory sensitivity, detection, identification, and self-evaluation of intensity/pleasantness.
  • Included healthy controls (N=58) and patient groups: depressive (N=49), anorectic (N=17), and alcohol/drug addiction (N=21).

Main Results:

Related Experiment Videos

  • Depressive patients: poor sensitivity/detection, over-evaluated pleasantness.
  • Anorectic patients: high sensitivity, over-evaluated intensity, under-evaluated pleasantness.
  • Alcohol/drug addicted patients: impaired odor identification.

Conclusions:

  • Despite shared depressive components, psychiatric diseases exhibit divergent olfactory impairments.
  • Olfactory deficits, particularly in emotional/cognitive aspects, suggest involvement of specific brain structures and processes.