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[Experimental study on anti-DHBV effect of yu gan capsules]
Xinghua Tan1, Aimin Zhang, Weihua Yu
1The Eighth People' s Hospital of Guangzhou, Guangzhou.
Objective:
To observe the antiviral effect of Yu Gan capsules against DHBV in ducks.
Methods:
50 Guangzhou brown spot ducks were used in this experiment. After the ducks were infected DHBV, they were divided into four groups at random (ACV 200 mg/kg group, Yu Gan capsules 6.5 g/kg group, Yu Gan capsules 3.25 g/kg group and virus control group) and Drugs were given by stomach once a day. Blood samples were taken from each duck and tested for DHBV-DNA's level. Researches left liver tissue were, sheared and used for optical analysis.
Results:
In Yu Gan capsules 6.5 g/kg group, DHBV-DNA's level in ducks' serum decreased on the 5th and 10th days after treatment and the 3th day after recession of treatment. There was a significant difference in the DHBV-DNA's level between the days after treatment and before treatment. there was also significant difference in the DHBV-DNA's level between Yu Gan capsules 6. 5 g/kg group and virus control group (P <0.01). Whereas, no inhibition effect was found in Yu Gan capsules 3.25 g/kg group.
Conclusion:
Yu Gan capsules have functions on anti-DHBV in duck.
