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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Synovial sarcoma of the frontal sinus. Case report

Gary L Gallia1, Daniel M Sciubba, Christine L Hann

  • 1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

Journal of Neurosurgery
|December 31, 2005
PubMed

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...