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Updated: Aug 14, 2026

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Claisen-type condensation of vinylogous acyl triflates
Shin Kamijo1, Gregory B Dudley
1Department of Chemistry and Biochemistry, Florida State University, Tallahassee, 32306-4390, USA.
Abstract:
[reaction: see text] The Claisen-type condensation reaction of cyclic vinylogous carboxylic acid triflates with lithium enolates and their analogues produces acyclic alkynes bearing a 1,3-diketone-type moiety. The present transformation is proposed to proceed via a 1,2-addition of the enolate to the vinylogous acyl triflate, followed by fragmentation of the aldolate intermediate.
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