Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HvrBase++: a phylogenetic database for primate species.

Jochen Kohl1, Ingo Paulsen, Thomas Laubach

  • 1Heinrich-Heine-University Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany.

Nucleic Acids Research
|December 31, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic GC bias correction improves species abundance estimation from metagenomic data.

Nature communications·2025
Same author

GTestimate: improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator.

GigaScience·2025
Same author

Quantitative profiling of human brain organoid cell diversity across four protocols and multiple cell lines.

Cell reports·2025
Same author

Gentrius: Generating Trees Compatible With a Set of Unrooted Subtrees and its Application to Phylogenetic Terraces.

Molecular biology and evolution·2024
Same author

A novel approach for in vivo DNA footprinting using short double-stranded cell-free DNA from plasma.

Genome research·2024
Same author

Splice_sim: a nucleotide conversion-enabled RNA-seq simulation and evaluation framework.

Genome biology·2024
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

HvrBase++ enhances primate and human DNA sequence data, including mitochondrial and chromosomal loci. This updated database offers improved data integrity and interactive geographical mapping for genetic research.

Area of Science:

  • Genetics and Genomics
  • Bioinformatics
  • Population Genetics

Background:

  • HvrBase++ is an updated and expanded version of the HvrBase database.
  • The database focuses on hypervariable regions (HVRI and HVRII) and includes broader genomic data.

Purpose of the Study:

  • To enhance the HvrBase database with more population-based sequence samples from primates and humans.
  • To improve data accuracy and accessibility for genetic research.
  • To introduce new features like interactive geographical mapping.

Main Methods:

  • Incorporated extensive population-based sequence samples from primates and humans.
  • Included complete mitochondrial genomes and sequences from X-chromosomal and autosomal loci.
  • Developed an automated procedure to monitor GenBank for data updates and ensure accuracy.

Related Experiment Videos

Main Results:

  • The collection now comprises 13,873 HVRI sequences, 4940 HVRII sequences, 1376 complete mitochondrial genomes, and hundreds of chromosomal sequences.
  • Implemented a data monitoring system to prevent erroneous data introduction.
  • Introduced an interactive graphical tool for accessing data via geographical maps.

Conclusions:

  • HvrBase++ provides a comprehensive and reliable resource for genetic research.
  • The database facilitates easy access to diverse genetic data, including geographical and population information.
  • The interactive mapping tool enhances data exploration and analysis capabilities.