Depressive symptoms in elderly patients after a somatic illness event: prevalence, persistence, and risk factors

Peter de Jonge1, Gertrudis I J M Kempen, Robbert Sanderman

  • 1Dept. of Psychiatry, Univ. of Groningen, The Netherlands. p.de.jonge@med.rug.nl

Psychosomatics
|December 31, 2005
PubMed

Insights

Elderly patients experiencing major health events like heart attack or cancer face a high risk of depression. Neuroticism is a key factor predicting both the onset and persistence of these depressive symptoms.

Area of Science:

  • Geriatric Medicine
  • Psychiatry
  • Public Health

Background:

  • Elderly individuals with somatic illnesses have an elevated risk for depression.
  • Understanding the prevalence and risk factors for depression post-somatic events is crucial for geriatric care.

Purpose of the Study:

  • To investigate the prevalence and persistence of depressive symptoms in elderly patients during the first year after myocardial infarction, congestive heart failure, fall-related injury, or cancer diagnosis.
  • To identify pre-event risk factors associated with developing and sustaining depressive symptoms.

Main Methods:

  • The GLAS study analyzed data from 614 elderly patients experiencing specific somatic events.
  • Follow-up assessments occurred at 8 weeks, 6 months, and 1 year post-event.
  • Twenty-one baseline risk factors were evaluated for their association with depressive symptoms.

Main Results:

  • Depressive symptoms were observed in 38.3% of patients during the post-event year, with 19.1% experiencing mild symptoms.
  • Depressive symptoms persisted in 67.5% of patients.
  • Significant pre-event risk factors included baseline depressive symptoms, age, smoking, poor general health, poor well-being, and neuroticism.

Conclusions:

  • Neuroticism emerged as a significant predictor for both the occurrence and persistence of post-event depressive symptoms.
  • The findings suggest that neuroticism may indicate a predisposition to depression in elderly patients facing significant health challenges.
  • Targeting neuroticism could be a strategy for managing depression in this vulnerable population.

Related Concept Videos

Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness, disability,...