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Durability of aneurysm embolization with matrix detachable coils
David Fiorella1, Felipe C Albuquerque, Cameron G McDougall
1Department of Neurosurgery and Neuroradiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. david.fiorella@adelphia.net
Neurosurgery
|December 31, 2005
Summary
Matrix detachable coils (MDC) showed a high recanalization rate in aneurysm embolization without stent support. These rates were comparable to or worse than bare platinum coils, often requiring retreatment.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Vascular Surgery
Background:
- Matrix detachable coils (MDC) are platinum coils coated with a bioabsorbable polymer.
- Animal models suggested MDC promote stable intra-aneurysmal scar tissue formation.
- This study assessed the durability of aneurysm occlusion using MDC.
Observation:
- A total of 131 aneurysms were embolized with MDC over 20 months.
- Follow-up data were available for 82 aneurysms.
- Patients with Neuroform stents were excluded.
Findings:
- 36.6% of aneurysms showed recanalization, with 23.1% requiring retreatment.
- Small aneurysms with small necks had a 26.1% recanalization rate.
- Large aneurysms had a significantly higher recanalization rate of 75%.
Implications:
- Aneurysms treated with MDC alone demonstrate a significant rate of recanalization.
- Recanalization rates were comparable to or worse than bare platinum coils.
- Many recanalizations necessitated retreatment, highlighting durability concerns.
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