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Lipid levels in Nepalese population.

D B Karki1, A Neopane, B Pradhan

  • 1Department of Medicine, Kathmandu Medical College, Teaching Hospital.

Kathmandu University Medical Journal (KUMJ)
|January 3, 2006
PubMed
Summary

In Nepalese adults, high triglyceride levels are the most common lipid abnormality. While high total cholesterol and LDL cholesterol are less common, they are notably elevated in the 40-49 age group.

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Area of Science:

  • Cardiovascular Health
  • Metabolic Disorders
  • Population Health

Background:

  • Lipid profiles are crucial indicators of cardiovascular health.
  • Understanding lipid patterns in specific populations, like the Nepalese, is vital for targeted health interventions.
  • Previous research on Nepalese lipid profiles is limited, necessitating this study.

Purpose of the Study:

  • To investigate the prevalence and patterns of lipid abnormalities in the Nepalese population.
  • To identify common lipid disorders and their distribution across different age groups.
  • To provide baseline data for public health strategies concerning dyslipidemia in Nepal.

Main Methods:

  • A retrospective analysis of 2218 fasting lipid profiles from patients attending the Temple of Healing.
  • Data collection involved reviewing blood samples for total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides.
  • Statistical analysis was performed to determine the prevalence of abnormal lipid levels.

Main Results:

  • Elevated triglyceride levels were highly prevalent, affecting 70% of subjects.
  • Abnormal total cholesterol (TC) was observed in 7.7% and high LDL cholesterol (LDL-C) in 5% of cases.
  • Low HDL cholesterol was found in 23% of the study population, with no significant age-related decrease.

Conclusions:

  • Abnormal triglyceride levels represent the most common lipid abnormality in the Nepalese population studied.
  • High total cholesterol and LDL cholesterol were less frequent but significantly elevated in the 40-49 age group.
  • HDL cholesterol levels showed resilience against age-related decline in this cohort.

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