Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Linking erectile dysfunction and coronary artery disease.

J J Rodriguez1, R Al Dashti, E R Schwarz

  • 1Division of Cardiology, The University of Texas Medical Branch, Galveston, 77555, USA.

International Journal of Impotence Research
|January 5, 2006
PubMed
Summary

Coronary artery disease (CAD) and erectile dysfunction (ED) share common vascular risk factors and endothelial dysfunction as a primary cause. This review explores the role of endothelial dysfunction in both conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Astrocytes at the crossroads of obstructive sleep apnea and Alzheimer's disease: from oxygen sensing to neurodegeneration.

Sleep & breathing = Schlaf & Atmung·2026
Same author

Early PSA-NCAM reduction in the dentate gyrus and impaired plasticity in the Alzheimer´s disease 3xTg-mice model.

Acta histochemica·2024
Same author

Entorhinal cortex astrocytic atrophy in human frontotemporal dementia.

Brain structure & function·2024
Same author

Adsorption of 2,4-dichlorophenoxyacetic acid on activated carbons from macadamia nut shells.

Environmental research·2024
Same author

Astrocyte S100β expression and selective differentiation to GFAP and GS in the entorhinal cortex during ageing in the 3xTg-Alzheimer's disease mouse model.

Acta histochemica·2023
Same author

Prominent and conspicuous astrocyte atrophy in human sporadic and familial Alzheimer's disease.

Brain structure & function·2023

Area of Science:

  • Cardiovascular Medicine
  • Urology
  • Vascular Biology

Background:

  • Coronary artery disease (CAD) and erectile dysfunction (ED) are prevalent and often coexist.
  • Shared vascular risk factors suggest a common underlying systemic vascular disease.
  • Endothelial dysfunction is a known contributor to CAD and is increasingly recognized in ED.

Purpose of the Study:

  • To review the role of the vascular endothelium in health and disease.
  • To examine how vascular risk factors induce endothelial dysfunction.
  • To discuss clinical trials investigating endothelial dysfunction in ED.

Main Methods:

  • Literature review of existing studies on CAD, ED, and endothelial function.
  • Analysis of the pathophysiology linking vascular risk factors to endothelial dysfunction.

Related Experiment Videos

  • Synthesis of findings from clinical trials on endothelial dysfunction and ED.

    • Main Results:

    • Endothelial dysfunction is a common pathological mechanism in both CAD and ED.
    • Vascular risk factors like diabetes, hypertension, hyperlipidemia, obesity, and smoking contribute to endothelial dysfunction.
    • Nitric oxide-mediated vasodilation, crucial for erectile function, is impaired by endothelial dysfunction.

    Conclusions:

    • Endothelial dysfunction is a unifying pathological pathway for CAD and ED.
    • Managing vascular risk factors is critical for addressing both conditions.
    • Further research and clinical trials are needed to fully elucidate the role of endothelial dysfunction in ED.