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Outbreak of Shigella sonnei gastroenteritis in Northeastern Taiwan

Yu-Yu Chuang1, Yhu-Chering Huang, Seng-Yi Lin

  • 1Departments of Pediatrics, St. Mary's Hospital, Lo-Tung, I-lan, Taiwan. ychuang@adm.cgmh.org.tw

The Pediatric Infectious Disease Journal
|January 6, 2006
PubMed

Insights

Shigella sonnei outbreaks in children show high resistance to common antibiotics like nalidixic acid. Ciprofloxacin remained effective, highlighting the importance of appropriate antibiotic selection to prevent prolonged shedding.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Gastroenteritis outbreaks caused by Shigella sonnei pose a significant public health challenge, particularly in pediatric populations.
  • Antibiotic resistance in bacterial pathogens is a growing global concern, complicating treatment strategies.

Purpose of the Study:

  • To investigate the antibiotic resistance patterns of Shigella sonnei isolates during a pediatric gastroenteritis outbreak.
  • To assess the susceptibility of these isolates to commonly used and newer antibiotics.

Main Methods:

  • Clinical isolates from a Shigella sonnei outbreak in Taiwan were collected and identified.
  • Antibiotic susceptibility testing was performed using standard microbiological methods.

Main Results:

  • A high prevalence of resistance was observed against nalidixic acid (98%), trimethoprim-sulfamethoxazole (97.5%), ampicillin (32%), and ceftriaxone (27%).
  • All Shigella sonnei isolates remained susceptible to ciprofloxacin, indicating its potential efficacy.

Conclusions:

  • The study highlights the emergence of multidrug-resistant Shigella sonnei strains.
  • Appropriate antibiotic selection, such as using ciprofloxacin, is crucial to effectively manage Shigella infections and prevent prolonged fecal shedding.

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