Modafinil attenuates disruptions in cognitive performance during simulated night-shift work

Carl L Hart1, Margaret Haney, Suzanne K Vosburg

  • 1Department of Psychiatry, Division on Substance Abuse, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA. clh42@columbia.edu

Summary

Modafinil improved cognitive performance and mood in shift workers during night shifts. However, higher doses of modafinil caused sleep disturbances during day shifts, indicating a trade-off.

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