Four-base codon mediated mRNA display to construct peptide libraries that contain multiple nonnatural amino acids

Norihito Muranaka1, Takahiro Hohsaka, Masahiko Sisido

  • 1Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Japan.

Nucleic Acids Research
|January 7, 2006
PubMed
Summary

This study expands mRNA display to create peptide libraries with nonnatural amino acids using four-base codons. This method generates diverse peptide ligands for novel biomolecule binding applications.

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