Related Experiment Video
Updated: Aug 13, 2026

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement
Published on: July 21, 2023
[Metabolism of alveolar bone]
Takashi Ikeo1, Seiji Goda, Eisuke Domae
1Department of Biochemistry, Osaka Dental University.
None:
The alveolar bone is a special tissue originating from the dental sac. This bone is constantly subjected to mechanical stress such as occlusal pressure and it responds to chronic inflammatory stimuli. Furthermore, the alveolar bone proper contains Sharpey's fibers (collagen) having a very short biological metabolic half-life of one day. In this manner, because the local environment of the alveolar bone is markedly different from that of other bones, the metabolic mechanism of the alveolar bone, and the alveolar bone proper in particular, may be different from that of other bones.
Related Concept Videos
Bone Remodeling
Osteoclasts in Bone Remodeling
The Bone Matrix
Bone Cells and Tissue
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the periosteum and...
What is Metabolism?
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
