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Central neurocytoma: report of two cases
Guilherme Borges1, Hoyama Costa Pereira, Edmur Franco Carelli
1Discipline of Neurosurgery, School of Medicine, State University of Campinas, Campinas, SP, Brazil.
Introduction:
Central neurocytomas are rare neuroectodermal tumors believed to arise from the subependymal matrix of the lateral ventricles.
Case Reports:
A 26-year-old woman and a 33-year-old man each had a large, heterogeneous, contrast enhancing mass in the lateral ventricles at the foramen of Monro causing bilateral hydrocephalus. The woman died after surgery, but the man is asymptomatic after three years.
Histopathology:
Both tumors were composed of isomorphic rounded cells positive for synaptophysin, chromogranin and NSE, while some reacted for GFAP, vimentin and S-100 protein. Electron microscopy revealed neuropil-like tissue between cells, but synapses were rare.