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Nebulin: does it measure up as a ruler?
Velia M Fowler1, Caroline R McKeown, Robert S Fischer
1Department of Cell Biology- CB163, The Scripps Research Institute, La Jolla, CA 92037, USA.
Abstract:
A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the pointed end of actin filaments in striated muscle.
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