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Updated: Jun 29, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
A new flavanoid from the flowers of Azadirachta indica
Bina S Siddiqui1, Syed Tariq Ali, Syed Kashif Ali
1H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. bina@khi.comsats.net.pk
Abstract:
Studies on the chemical constituents of the flowers of Azadirachta indica have led to the isolation of one new flavanone named as azharone (5,7,4'-trihydroxy-3'-(3''-methyl-2'',3''-epoxybutyl)flavan-4-one (3)) along with two known constituents azadirone (1), and isoazadironolide (2). Their structures have been elucidated through spectral studies including 2D-NMR (COSY-45, NOESY, J-resolved, HMQC, HMBC) experiments.
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