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Neurotrophins in autoimmune diseases: possible implications for alopecia areata

T N Palkina1, A A Sharov, T Y Sharov

  • 1Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA.

The Journal of Investigative Dermatology. Symposium Proceedings
|January 13, 2006
PubMed
Abstract

No abstract available in PubMed .

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Enzyme-linked Receptors01:00

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Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...

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