Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Unilateral amiodarone keratopathy.

Michael N Chilov, Con N Moshegov, Frances Booth

    Clinical & Experimental Ophthalmology
    |January 13, 2006
    PubMed
    Summary

    Amiodarone can cause vortex keratopathy, a common eye condition with superficial corneal deposits. This case study presents an unusual unilateral presentation in an elderly woman, exploring potential causes for the asymmetry.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Visual outcomes after implantation of a low-add (+3.25D) diffractive multifocal intraocular lens.

    Clinical & experimental ophthalmology·2015
    Same author

    Wavefront-guided myopic femto-LASIK based on measurements with a new Hartmann-Shack aberrometer.

    Clinical & experimental ophthalmology·2014
    Same author

    Primary trabeculectomy with mitomycin C: safety and efficacy at 2 years.

    Clinical & experimental ophthalmology·2010
    Same author

    Postoperative Mycobacterium abscessus nodular conjunctivitis.

    Clinical & experimental ophthalmology·2008
    Same author

    Bevacizumab (Avastin) for the treatment of neovascular glaucoma.

    Clinical & experimental ophthalmology·2007
    Same author

    Amadeus microkeratome: experience with the first 2000 cases and lessons learned.

    Clinical & experimental ophthalmology·2005

    Area of Science:

    • Ophthalmology
    • Pharmacology
    • Corneal Diseases

    Background:

    • Vortex keratopathy is a known ocular side effect of amiodarone treatment.
    • It typically presents as bilateral, symmetrical superficial corneal deposits in a characteristic vortex pattern.
    • This condition is frequently observed in patients undergoing amiodarone therapy for cardiac arrhythmias.

    Observation:

    • An unusual case of unilateral amiodarone vortex keratopathy was observed in an elderly female patient.
    • The affected eye displayed superficial corneal deposits in a vortex pattern.
    • The fellow eye exhibited corneal dysplasia, suggesting a potential contributing factor to the unilateral presentation.

    Findings:

    • The study presents a rare instance of asymmetric amiodarone-induced vortex keratopathy.
    • Pathophysiological mechanisms underlying amiodarone keratopathy are discussed.
    • A specific hypothesis is proposed to explain the unilateral occurrence in this patient.

    Implications:

    • This case highlights the potential for asymmetric drug-induced ocular toxicity.
    • Understanding the factors contributing to unilateral amiodarone vortex keratopathy may refine patient monitoring.
    • Further research into drug-specific corneal deposition patterns is warranted.

    Related Experiment Videos