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Frontal fibrosing alopecia.
Lesley Clark-Loeser1, Jo-Ann Latkowski
1Department of Dermatology, New York University School of Medicine, USA.
Dermatology Online Journal
|January 13, 2006
Summary
Frontal fibrosing alopecia, a condition causing eyebrow and hairline loss, was diagnosed in a 75-year-old woman. Standard treatments proved ineffective for her progressive hair loss.
Area of Science:
- Dermatology
- Pathology
Background:
- Frontal fibrosing alopecia (FFA) is an increasingly recognized form of scarring alopecia.
- It is characterized by progressive loss of the frontal hairline and eyebrows.
Observation:
- A 75-year-old woman experienced a 3-year history of progressive eyebrow hair loss and frontal-parietal hairline recession.
- Histopathologic examination of biopsy specimens confirmed lichen planopilaris.
Findings:
- The patient's clinical presentation and biopsy results led to a diagnosis of frontal fibrosing alopecia.
- Despite treatment with topical glucocorticoids, intralesional triamcinolone, and tacrolimus ointment, her hair loss did not improve.
Implications:
- This case highlights the potential refractoriness of frontal fibrosing alopecia to conventional therapies.
- Further research into novel treatment strategies for FFA is warranted.