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Updated: Aug 13, 2026

fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals
Published on: May 23, 2017
From deafness genes to hearing mechanisms: harmony and counterpoint
1Unité de Génétique des Déficits Sensoriels, INSERM U587, Institut Pasteur, 25 rue du Dr Roux, F-75724 Paris cedex 15, France. cpetit@pasteur.fr
Abstract:
The study of hereditary hearing impairments provides a unique opportunity to deal with two objectives simultaneously: (i) identification of the causative genes and the underlying pathogenic process in each form of deafness; and (ii) elucidation of the molecular and cellular mechanisms of hearing. This review highlights the breakthroughs achieved during the past 12 years, with respect to their medical impacts and advances in basic scientific knowledge. To date, this research relies extensively on mouse models to study human forms of deafness. But, can mouse models sustain genetic approaches to study the physiology and pathophysiology of the auditory system and to develop and test drugs?
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