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Progress in understanding the nicotinic acetylcholine receptor function at central and peripheral nervous system
1Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine.
Maryland Medical Journal (Baltimore, Md. : 1985)
|July 1, 1992
Abstract:
The need to treat diseases affecting the nicotinic AChR is great, but therapeutic options are few. Through careful correlation of structure-activity relationships of AnTX analogs, we may ultimately be led to the development of diagnostic and therapeutic drugs with specific nicotinic agonist or antagonist activities in the central nervous system that would be of major importance in the treatment of Alzheimer's disease.