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Updated: Aug 13, 2026
07:56
Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
Published on: May 5, 2023
[Human blood vascular endothelial dysfunction in HIV infection]
Voprosy Virusologii
|January 18, 2006
Summary
Human immunodeficiency virus (HIV) impacts blood vessel coagulation and endothelial cells. This review explores HIV
Area of Science:
- Vascular biology
- Infectious diseases
- Cellular biology
Context:
- Human immunodeficiency virus (HIV) infection affects multiple organ systems.
- Endothelial cells play a critical role in vascular health and disease.
- The interaction between HIV and the endothelium is complex and multifaceted.
Purpose:
- To review the impact of HIV on the blood coagulative system.
- To examine the potential for endothelial cell infection by HIV.
- To discuss mechanisms of angiogenesis and apoptosis in HIV-infected endothelial cells.
Summary:
- HIV infection influences the coagulative system and can infect endothelial cells in vivo and in vitro.
- Mechanisms of HIV-induced angiogenesis and apoptosis in cultured endothelial cells are discussed.
- The review synthesizes current knowledge on HIV's effects on vascular endothelium.
Impact:
- Understanding HIV's vascular effects can inform therapeutic strategies.
- This review highlights the importance of targeting endothelial dysfunction in HIV management.
- Provides insights into the cellular and molecular mechanisms underlying HIV-associated vascular complications.
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