Related Experiment Video
Updated: Aug 13, 2026

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
Reliability of a noninvasive device to measure systemic hemodynamics in hemodialysis patients
Shaheen Motiwala1, Ursula C Brewster, Mark A Perazella
1Section of Nephrology, Yale University, New Haven, Connecticut, USA.
Objective:
To evaluate the reliability of a noninvasive hemodynamic monitor in hemodialysis patients.
Methods:
We enrolled 15 male patients (mean age 63+/-12 years) on stable chronic hemodialysis. Blood pressure and hemodynamic readings were obtained with the Dynapulse 500 Guardian device (Pulsemetric Inc., San Diego, California, USA), which measures systemic hemodynamics on the basis of oscillometric waveforms obtained through a cuff placed over the brachial artery. Measurements were taken sequentially, in duplicate, before, during and after hemodialysis, in the supine, seated and standing positions on four separate midweek dialysis sessions over a 2-week period.
Results:
The repeatability of the method was tested using 200 pairs of valid measurements. The average values (+/-SD) were 137+/-22 mmHg for systolic blood pressure, 80+/-13 mmHg for diastolic blood pressure, 76+/-15 bpm for heart rate, 1320+/-268 mmHg/s for dP/dtmax, 2.8+/-0.5 l/min/m for cardiac index, and 1455+/-359 dyn/s/cm for systemic vascular resistance. The mean differences (+/-SD of the difference) between readings were 0.1+/-10.4 mmHg for systolic blood pressure, 0.3+/-6.0 mmHg for diastolic blood pressure, -0.2+/-8.0 bpm for heart rate, 0.2+/-234 mmHg/s for dP/dtmax, 0.03+/-0.26 l/min/m for cardiac index and -10+/-177 for systemic vascular resistance, yielding limits of agreement (95%) of -20 to 20 mmHg for systolic blood pressure, -11 to 12 mmHg for diastolic blood pressure, -16 to 17 bpm for heart rate, -458 to 458 mmHg/s for dP/dtmax, -0.5 to 0.5 l/min/m for cardiac index and -338 to 357 dyn/s/cm for systemic vascular resistance. Other hemodynamic parameters fared similarly, and coefficients of variation were all between 7 and 18%.
Conclusion:
We conclude that the Dynapulse 500 Guardian has adequate reliability indices in hemodialysis patients.
Related Concept Videos
Hemodialysis II: Procedure and Complications
Hemodialysis I: Introduction
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Assessing Blood pressure using a doppler ultrasound
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
