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The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Cardiac angiosarcoma
Gayathri P Amonkar1, Jaya R Deshpande
1T.N. Medical College and B.Y.L. Nair Hospital, Bombay Central, Mumbai 400-008, India. ppamonkar@hotmail.com
Abstract:
Primary tumors of the heart are extremely rare, with a prevalence rate of around 0.01% in collective autopsy studies. Majority of the primary cardiac tumors are benign. Myxoma is the most common primary cardiac tumor, while angiosarcoma is the commonest primary malignant tumor. We present a case report of a 20-year-old patient with history of breathlessness and hemoptysis. A malignant mass was seen arising in the right atrium, with pericardial effusion and multiple metastases in the lung. A complete autopsy was performed and a diagnosis of cardiac angiosarcoma was confirmed on histology and immunohistochemistry.