Quality assurance in nuclear medicine--biological quality control of radiopharmaceuticals

Quality assurance is the sum of all parameters concerning the preparation and control of a finished product. It is a wide term commonly used for the confirmation and validity of various ways and measurements adopted to obtain a high quality procedure for intended use with guaranteed performance. Biological quality control of pharmaceutical products becomes essential as they are ultimately to be consumed by living organisms, in particular the humans. In this review, we have discussed the importance and significance of biological quality control in nuclear medicine. The current and new procedures for sterility, apyrogenecity and the biodistribution quality control, have been discussed and evaluated in view of the future needs and modern trends in this important area of research.