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Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Family history may be misleading in the diagnosis of Dent's disease
F Anglani1, P Bernich, E Tosetto
1Department of Medical and Surgical Sciences, Laboratory of Molecular Biology, University of Padova, Padova, Italy.
Abstract:
The rare Dent's disease manifests with medullary nephrocalcinosis, nephrolithiasis, hypercalciuria, low molecular weight proteinuria and other tubular dysfunctions, rickets or osteomalacia, and renal failure, in various combinations. It is a recessive X-linked condition. Clinicians consider family history a fundamental pointer to its diagnosis, but this is not invariably the case as clearly pointed out by the two reported cases.
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