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Artecoll: the Arizona experience and lessons learned
Millard P Thaler1, Zeena I Ubogy
1Papillon Cosmetic Dermatology Center, Mesa, Arizona, USA. papillondermol@yahoo.com
Summary
Artecoll offers effective, long-lasting wrinkle correction, demonstrating high patient acceptance. While generally safe, persistent nodules occurred in a few cases, highlighting a learning curve for this permanent filler.
Area of Science:
- Dermatology
- Cosmetic Surgery
- Medical Aesthetics
Background:
- Artecoll is a novel soft tissue augmenting agent entering the U.S. market.
- Soft tissue fillers are increasingly utilized for cosmetic facial rejuvenation.
Purpose of the Study:
- To compare the safety and efficacy of Artecoll versus Zyderm/Zyplast for facial wrinkle correction.
- To document practical insights gained from using Artecoll as a dermal filler.
Main Methods:
- A randomized study involving 38 patients comparing Artecoll with Zyderm/Zyplast injections.
- Evaluations of wrinkle improvement by patients, treating physicians, and masked evaluators.
- Monitoring of adverse events and patient acceptance.
Main Results:
- Artecoll was perceived as superior to collagen fillers in most facial areas, except for the glabella and upper lip.
- Adverse effects were comparable to collagen, with most being minor.
- Three patients experienced treatable persistent nodules, primarily in perioral areas.
Conclusions:
- Artecoll demonstrates effectiveness, longevity, and safety for treating facial wrinkles and folds.
- High patient acceptance rates were observed with Artecoll treatment.
- A learning curve exists for injecting Artecoll due to its thicker, more permanent nature.
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