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Related Experiment Videos

Tooth loss and obstructive sleep apnoea.

Caterina Bucca1, Alessandro Cicolin, Luisa Brussino

  • 1Department of Biomedical Sciences and Human Oncology, University of Turin, Italy. caterina.bucca@unito.it

Respiratory Research
|January 19, 2006
PubMed
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Complete tooth loss (edentulism) significantly increases the risk of obstructive sleep apnea (OSA). Not wearing dentures narrows the airway, worsening sleep apnea severity and inflammation markers.

Area of Science:

  • Dental Medicine
  • Sleep Medicine
  • Respiratory Medicine

Background:

  • Complete tooth loss (edentulism) can alter upper airway anatomy and function.
  • The relationship between edentulism and obstructive sleep apnea (OSA) requires further investigation.

Purpose of the Study:

  • To evaluate if edentulism contributes to the development of obstructive sleep apnea (OSA).

Main Methods:

  • Polysomnography was conducted on 48 edentulous subjects over two nights, with and without dentures.
  • Upper airway dimensions were assessed via cephalometry and forced mid-inspiratory airflow rate (FIF50).
  • Exhaled nitric oxide (eNO) and oral nitric oxide (oNO) were measured as indicators of airway inflammation.

Main Results:

Related Experiment Videos

  • The apnea-hypopnea index (AHI) was significantly higher without dentures (17.4) compared to with dentures (11.0).
  • Removing dentures reduced retropharyngeal space and increased AHI in 71% of subjects, versus 48% with dentures.
  • Higher eNO and oNO levels were observed after sleeping without dentures, indicating increased airway inflammation.

Conclusions:

  • Complete tooth loss appears to promote upper airway obstruction during sleep.
  • Reduced retropharyngeal space and elevated nitric oxide levels are associated with edentulism-related sleep apnea.
  • Wearing dentures may mitigate the adverse effects of edentulism on sleep-disordered breathing.