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[Viral safety concept: application to blood and blood products]

Jean-Hugues Trouvin1

  • 1Direction de l'évaluation des medicaments et produits biologiques (Demeb), Agence française de sécurité sanitaire des produits de santé (Afssaps), 143, boulevard Anatole France, 93285 Saint-Denis Cedex. Jean-Hugues.TROUVIN@afssaps.sante.fr

La Revue Du Praticien
|January 20, 2006
PubMed

Safety of blood and its derivatives, with regards to the risk of transmission of infectious agents such as viruses or non conventional agents, relies on a series of general principles for which national and European guidance and regulations have been drawn and regularly updated. Three main criteria contribute to the safety of these products: knowledge and control of the quality of blood or plasma as the starting material, the efficiency of the manufacturing process to remove/inactivate adventitious agents, and the testing done during the production process. In addition, vigilance routinely exercised on the products used in daily practice increases the confidence in these health products.

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