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Updated: Aug 13, 2026

Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
Enteric microbial flora, bacterial overgrowth, and short-bowel syndrome
John K Dibaise1, Rosemary J Young, Jon A Vanderhoof
1Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona 85259, USA. dibaise.john@mayo.edu
Abstract:
Small intestinal bacterial overgrowth (SIBO) occurs commonly in short-bowel syndrome (SBS) and, in some instances, may result in significant problems. SIBO is characterized by a variety of signs and symptoms resulting from nutrient malabsorption caused by an increased number and/or type of bacteria in the small intestine. The anatomic and physiologic changes that occur in SBS together with medications commonly used in these patients facilitate the development of SIBO. Because many aspects related to SIBO in the SBS population remain poorly understood, it was our aim to review the current understanding of the gut flora and issues related to SIBO occurring in SBS.
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