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Updated: Aug 6, 2026

Gonadectomy and Blood Sampling Procedures in the Small Size Teleost Model Japanese Medaka (Oryzias latipes)
Published on: December 11, 2020
[Several indicators of hormonal homeostasis (hypophysis--gonads) in patients with hypertension]
Abstract:
One hundred and sixty-three male patients with essential hypertension (EH) stage I (68 subjects) and II (95 subjects) were compared to healthy controls by concentrations of renin, aldosterone, LH, FSH, prolactin and estradiol assessed by means of radioimmunoassay. The findings show that unlike healthy controls EH patients have low levels of LH and testosterone, high prolactin and unchanged FSH and estradiol concentrations. The involutional dynamics is similar for patients and controls: dissociation in the levels of hypophyseal hormones and testosterone. An age-specific trend in prolactinemia was related to EH severity.
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