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Updated: Aug 13, 2026

Murine Model of Intestinal Ischemia-reperfusion Injury
Published on: May 11, 2016
[Cytomegalovirus enterocolitis: a rare cause of gastrointestinal ischemia and bleeding]
Raphaël Vialle1, Gaëlle Burdy, Olivier Drain
1Service de Chirurgie Générale et Digestive, Hôpital Foch, Suresnes.
Abstract:
Cytomegalovirus (CMV) infections are frequent in patients with severe immunodeficiency. We report a case of isolated digestive localization in a young woman initially non-immunocompromised. Initially, she was admitted in the intensive-care unit for a severe post-operative shock secondary to a respiratory distress syndrome. She then developed severe enterocolitis which was initially unexplained. Outcome was favorable but digestive perforations required multiple surgical digestive resections. The histological diagnosis was confirmed by immunofluorescence staining and the antigenemia and specific antibodies kinetics. We emphasize the various characteristics of this pathology and point out the risk of missing this unusual cause of digestive perforation and severe bleeding.
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