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Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Practical preparation method of polymer-incarcerated (PI) palladium catalysts using Pd(II) salts
Hiroyuki Hagio1, Masaharu Sugiura, Shū Kobayashi
1Graduate School of Pharmaceutical Sciences, The University of Tokyo, The HFRE Division, ERATO, Japan Science and Technology Agency (JST), Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Abstract:
[reaction: see text]. Polymer-incarcerated (PI) palladium catalyst was practically prepared from inexpensive Pd(II) salts and a polystyrene-based copolymer under reducing conditions. Remarkable effects of alkali metal salts on the palladium loading were observed. PI Pd thus prepared showed high catalytic activity in Mizoroki-Heck reactions and Suzuki-Miyaura couplings with a range of substrates including an aryl chloride. In all cases, the Pd catalyst was recovered quantitatively without leaching, and reused several times without significant loss of activity.

![Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F51444.jpg&w=3840&q=50)