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Control of acute myeloid leukemia morbidity in northwest Iran
1Ghazi Hematology Oncology Research Department, Tabriz University of Medical Sciences, Iran 51665-139. jeziaei@yahoo.com
Background:
To investigate protocols of remission induction therapy for prevention of morbidity of acute myeloid leukemia.
Materials And Methods:
The responses of 150 patients to "2+5" and "3+7" protocols during 1996-2003 were assessed and analyzed with the Chi-Square method.
Results:
Complete remission was observed in 30% of cases treated with 2 days of daunorubicin and 5 days of cytarabine (2+5 regimen). Remission was increased to 52.5% when patients were treated with 3+7 regimens with the same drugs. Partial remission resulted in 25 and 10 percent of cases, respectively.
Conclusion:
As in previous studies the 3+7 regimen was demonstrated to be more effective than the 2+5 regimen in our hospital (p=0.0009).