[Diagnosis and surgical management of adult Hirschsprung disease]
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Updated: Aug 13, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Shu-qing Ding1, Yong-tian Chen, Yi-jiang Ding
1The Third Affiliated Hospital of Nanjing University of Chinese Traditional Medicine, Nanjing 210001, China. dingshuq@hotmail.com
Objective:
To investigate the diagnosis and surgical treatment of adult Hirschsprung disease (AHD).
Methods:
Clinical data of 10 patients with AHD undergoing operation from May 1985 to May 2005 were analyzed retrospectively.
Results:
There were 7 males and 3 females with an age ranged from 14 to 40 years. All the cases had constipation, and were diagnosed by barium enema. Aganglionosis was located in distal sigmoid and rectum in 2 cases, in rectum in 7 cases, unknown in one case. Colostomy was performed in one, Ikeda s operation in 6, Rehbein operation in two,modified Swenson operation in one. After radical operation,7 patients had excellent continence function, one had good function, one had poor function.
Conclusions:
The diagnosis of adult HD mainly depends on the history of constipation, barium enema and manometry examination. The pull-through procedures are effective surgical treatments for adult HD. The operation type should be selected individually.
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