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Effect of liniment levamisole on cellular immune functions of patients with chronic hepatitis B
Ke-Xia Wang1, Li-Hua Zhang, Jiang-Long Peng
1Department of Pathogenic Biology, School of Medicine, Anhui University of Science and Technology, Huainan 232001, Anhui Province, China. cpli@aust.edu.cn
Aim:
To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B.
Methods:
The levels of T lymphocyte subsets and mIL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole.
Results:
After one course of treatment with liniment levamisole, the levels of CD3(+), CD4(+), and the ratio of CD4(+)/CD8(+) increased as compared to those before the treatment but the level of CD8(+) decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole.
Conclusion:
Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.
