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Published on: June 27, 2025
Non-puerperal uterine inversion due to uterine sarcoma
Gennaro Cormio1, Vera Loizzi, Claudia Nardelli
1Department of Obstetrics and Gynecology, University of Bari, Via delle Murge 59/A, IT-70124 Bari, Italy. n.cormio@gynecology2.uniba.it
Gynecologic and Obstetric Investigation
|January 28, 2006
Summary
Non-puerperal uterine inversion is exceptionally rare, often linked to uterine sarcoma. This case highlights a potential association with malignant mixed Mullerian tumors, emphasizing the need for awareness in rare gynecological presentations.
Area of Science:
- Gynecologic Oncology
- Pathology
- Surgical Case Reports
Background:
- Uterine inversion is a rare obstetric complication, typically occurring postpartum.
- Non-puerperal uterine inversion is exceptionally uncommon, with few documented cases.
- Malignant conditions, such as uterine sarcoma, are rarely associated with non-puerperal uterine inversion.
Observation:
- A 79-year-old nulliparous woman presented with vaginal bleeding.
- Pelvic examination revealed a large cervical mass occluding the vagina.
- Diagnosis of uterine inversion was established, with the uterus not palpable rectally.
Findings:
- The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymph node sampling.
- Postoperative recovery was uneventful, with discharge on the 5th day.
- No recurrence was observed during a 19-month follow-up after pelvic radiation.
Implications:
- Chronic non-puerperal uterine inversion may be a rare complication of malignant mixed Mullerian tumors.
- This case underscores the importance of considering gynecologic malignancies in atypical presentations of uterine inversion.
- Further research is warranted to elucidate the relationship between uterine tumors and non-puerperal inversion.